Diagnostic Solutions Laboratory is pleased to offer you the GI Microbial Assay Plus (GI-MAP). The GI-MAP includes the first comprehensive pathogens assay that is FDA approved, the GPP assay by Luminex Corp. The pathogen targets include bacteria, parasites and another first for the market, viruses!
Using the same molecular technology, we have developed assays for microbes that are useful for integrative and function medicine practitioners. And unlike previous PCR assays, we have fully validated each target organism in our panel, so that you can have confidence in the results. The panel includes opportunistic organisms, normal flora, parasites, and fungi. DNA/PCR techniques also allow for the measurement of antibiotic resistance genes and virulence factors that contribute to pathogenicity. Both are used to help determine clinical significance and the most effective treatments.
Other available stool tests may appear to be DNA-based tests, but they are in fact using Matrix Assisted Laser Desorption/Ionization Time-of-Flight (MALDI-TOF) only to identify stool microbes. Their methodology relies on cultures from stool and are not molecular/PCR based assays. With a culture based test it is not possible to measure strict anaerobes, viruses or virulence factors. They also lack the ability to deliver true quantitation of any of the reported organisms.
Fecal zonulin testing is now available as an add-on to the GI-MAP.
Zonulin is a protein secreted by intestinal cells that regulates intercellular tight junctions. Tight junctions are the connections between epithelial cells that make up the gastrointestinal lining.Tight junctions can be opened or closed, depending on the physiological need.
Intestinal permeability, also known as “leaky gut,” has been associated with inflammatory bowel disease, celiac disease, food allergy, irritable bowel syndrome, critical illness, autoimmune diseases and obesity and metabolic disease (7). In many cases, permeability precedes disease.
Zonulin regulates barrier permeability. Certain gut bacteria and gliadin (the main staple protein from wheat) can activate the zonulin system.
Please note the following guidelines for lab test orders:
• Testing prices include domestic (US) shipping.
• We are unable to ship lab kits to PO boxes. Please use a residential address.
• Unfortunately this test is not available to residents of New York; any orders and/or samples originating from the state of New York will automatically be cancelled.
• We do not provide insurance billing for these tests. You will receive an invoice for your purchase for your records.
• Some lab providers fill out requisition forms ahead of time, with patient information. To avoid confusion when processing orders, if you are ordering lab kits for multiple people, we do request that you place a separate order for each person.
• Please note: after you order a test kit, completing the test is your responsibility. It is also your responsibility to have the test interpreted by a qualified professional.
• Due to the fees we incur after a test kit is sent, we are unable to offer returns or exchanges on test kits.
• Once you have sent in your lab kit, the lab will send us test results which we will forward to you. Please contact firstname.lastname@example.org with questions.